Because Diagenode has been focusing exclusively on epigenetics for 20 years, we can provide the highest quality epigenetics products for chromatin studies. We developed a wide range of solutions for a variety of sample types and inputs, with an emphasis on low input technologies. All these are provided with what you need to be able to master chromatin analysis: user-friendly protocols as well as options for numerous validation steps and complete workflows.

 

Take a look at this quick overview of how we can help you with your chromatin profiling project:

 

ATAC-seq

Assessment of open chromatin regions at single-nucleotide resolution

 

  • • Highly efficient isolation of nuclei with optimized protocols for cells and tissues
  • • Accurate library amplification with an intermediate quantification step
  • • High tagmentation reproducibility using Diagenode proprietary Tagmentase (Tn5 transposase)
  • • Accurate sequencing data with unique dual indexes to mitigate index hoping

 

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iDeal CUT&Tag

Accurate low-input chromatin profiling

 

  • • Validated for histone and some non-histone proteins
  • • High efficiency using proprietary Diagenode pA-Tn5
  • • Accurate library amplification with an intermediate quantification step
  • • Monitoring of assay efficiency by qPCR
  • • Accurate sequencing data with unique dual indexes to mitigate index hoping

 

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Chromatin immunoprecipitation

Genome-wide mapping of DNA–protein interactions

 

 

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Antibodies

Combine Diagenode antibodies with CUT&Tag and ChIP kits

 

  • • Validated in epigenetic applications, including ChIP, ChIP-seq, CUT&Tag
  • • Batch-specific validation data available on the website
  • • Guaranteed performance for tested applications

 

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Take advantage of our experience to get the most out of your experiments.

Schedule a call with one of our epigenomics application specialists and get a personalized offer for your research project.